HLA-DRB3 purified MaxPab mouse polyclonal antibody (B02P)
产品名称： HLA-DRB3 purified MaxPab mouse polyclonal antibody (B02P)
英文名称： HLA-DRB3 purified MaxPab mouse polyclonal antibody (B02P)
产品编号： H00003125-B02P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human HLA-DRB3 protein.
- Immunogen:
- HLA-DRB3 (NP_072049.2, 1 a.a. ~ 266 a.a) full-length human protein.
- Sequence:
- MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Flow Cytometry
enlarge this image- FACS analysis of negative control 293 cells (Black) and HLA-DRB3 expressing 293 cells (Green) using HLA-DRB3 purified MaxPab mouse polyclonal antibody.
- Western Blot (Tissue lysate)
- HLA-DRB3 MaxPab polyclonal antibody. Western Blot analysis of HLA-DRB3 expression in human liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of HLA-DRB3 expression in transfected 293T cell line (H00003125-T01) by HLA-DRB3 MaxPab polyclonal antibody.
Lane 1: HLA-DRB3 transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3125
- GeneBank Accession#:
- NM_022555
- Protein Accession#:
- NP_072049.2
- Gene Name:
- HLA-DRB3
- Gene Alias:
- HLA-DR3B,MGC117330
- Gene Description:
- major histocompatibility complex, class II, DR beta 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq
- Other Designations:
- MHC class II HLA-DR beta 3 chain,MHC class II antigen DR beta 3 chain,human leucocyte antigen DRB3
- Related Disease
- Abortion, Habitual
- Abruptio Placentae
- Alveolar Bone Loss
- Aortic Aneurysm, Abdominal
- Arthritis, Juvenile Rheumatoid
- Autoimmune Diseases
- Blood Group Incompatibility
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Bronchiolitis
- Carcinoma, Small Cell
- Cataplexy
- Chronic Disease
- Churg-Strauss Syndrome
- Dementia
- Diabetes, Gestational
- Disease Susceptibility
- Genetic Predisposition to Disease