IL4R MaxPab mouse polyclonal antibody (B01)
产品名称： IL4R MaxPab mouse polyclonal antibody (B01)
英文名称： IL4R MaxPab mouse polyclonal antibody (B01)
产品编号： H00003566-B01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human IL4R protein.
- Immunogen:
- IL4R (NP_001008699, 1 a.a. ~ 227 a.a) full-length human protein.
- Sequence:
- MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSNIC
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Flow Cytometry
enlarge this image- FACS analysis of negative control 293 cells (Black) and IL4R expressing 293 cells (Green) using IL4R purified MaxPab mouse polyclonal antibody.
- Western Blot (Transfected lysate)
- Western Blot analysis of IL4R expression in transfected 293T cell line (H00003566-T01) by IL4R MaxPab polyclonal antibody.
Lane 1: IL4R transfected lysate(24.97 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3566
- GeneBank Accession#:
- NM_001008699
- Protein Accession#:
- NP_001008699
- Gene Name:
- IL4R
- Gene Alias:
- CD124,IL4RA
- Gene Description:
- interleukin 4 receptor
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000122506,interleukin 4 receptor alpha chain,interleukin-4 receptor alpha chain
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