PCNA polyclonal antibody (A02)
产品名称: PCNA polyclonal antibody (A02)
英文名称: PCNA polyclonal antibody (A02)
产品编号: H00005111-A02
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant PCNA.
- Immunogen:
- PCNA (NP_002583, 152 a.a. ~ 261 a.a) partial recombinant protein with GST tag.
- Sequence:
- SHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Application Image
- ELISA
- Entrez GeneID:
- 5111
- GeneBank Accession#:
- NM_002592
- Protein Accession#:
- NP_002583
- Gene Name:
- PCNA
- Gene Alias:
- MGC8367
- Gene Description:
- proliferating cell nuclear antigen
- Omim ID:
- 176740
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
- Other Designations:
- DNA polymerase delta auxiliary protein,OTTHUMP00000030189,OTTHUMP00000030190,cyclin
- Interactome
- Related Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Colorectal Neoplasms
- Disease Progression
- DNA Damage
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Glioma
- Graft vs Host Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Laryngeal Neoplasms
- Lung Neoplasms
- Meningeal Neoplasms
- Meningioma